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For appropriate patients with type 2 diabetes…

Actor Portrayal.

aIMS Health, NPA Monthly, TRxs, October 2006 - August 2012.

  • Important Information

    JANUMET is indicated, as an adjunct to diet and exercise, to improve glycemic control in adults with type 2 diabetes mellitus when treatment with both sitagliptin and metformin is appropriate.

    JANUMET should not be used in patients with type 1 diabetes or for the treatment of diabetic ketoacidosis.

    JANUMET has not been studied in patients with a history of pancreatitis. It is unknown whether patients with a history of pancreatitis are at increased risk of developing pancreatitis while taking JANUMET.

  • Selected Important Risk Information


    Lactic acidosis is a rare but serious complication that can occur because of metformin accumulation. The risk increases with conditions such as sepsis, dehydration, excess alcohol intake, hepatic insufficiency, renal impairment, and acute congestive heart failure.

    The onset is often subtle, accompanied only by nonspecific symptoms such as malaise, myalgias, respiratory distress, increasing somnolence, and nonspecific abdominal distress.

    Laboratory abnormalities include low pH, increased anion gap, and elevated blood lactate.

    If acidosis is suspected, JANUMET should be discontinued and the patient hospitalized immediately [see Warnings and Precautions].

    View Additional Selected Important Risk Information

  • Support and Educational Materials for Patients

Formulary Coverage

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bFingertip Formulary®,
May, 2015. Percentages based on current enrollment.
cAmong oral antidiabetics and glucagon-like peptide-1s.